It may take up to a week for the doctor to know results from this biopsy test. How long is it before the result of the test is known? Must I do anything special after the test is over?Ĭall your doctor if you develop a fever of over 100 degrees F, or if you have vaginal bleeding that lasts longer than two to three days after any bleeding has stopped. Your doctor might order a pregnancy test before performing the biopsy. This test could end a very early pregnancy. It is extremely rare to have heavy bleeding or to develop an infection that needs treatment. You might have pelvic cramps (sometimes intense) during the procedure and sometimes for a day or two afterward you may also experience a small amount of vaginal bleeding. Some doctors will use a scraping instrument (“curette”) in place of a Pipelle. There are several variations in the way a doctor can do this procedure. The entire procedure takes about 10 minutes. To get a good sample, the doctor will then move the Pipelle forward and backward a few times before removing it. As the rod is pulled out, the Pipelle becomes hollow and creates suction, drawing some of the cells from the lining of your uterus into the Pipelle. Then the doctor pulls a thin wire out of the center of the Pipelle. The doctor inserts the Pipelle through the opening in your cervix and positions it several inches into the uterus. If your biopsy is being done with the most commonly used method, the doctor will use a flexible, sterile plastic instrument called a Pipelle, which looks like a drinking straw. In most cases the doctor will put a clamp on your cervix to hold it steady. After cleaning your vagina and cervix (the entrance to the uterus, visible from your vagina) with antibacterial soap, your doctor may inject a local anesthetic to numb your cervix. It is best to avoid tampon use and avoid using vaginal creams during the day leading up to the procedure. You will be asked to give a urine specimen before your procedure. You will need to take an NSAID, or medicine such as ibuprofen 400mg, one to two hours before the test, to reduce the possibility of uterine cramps during the procedure. Endometrial biopsy takes a tissue sample from the lining of your uterus (the endometrium) to evaluate it for problems, including endometrial cancer that might explain unusual bleeding. In general, doctors take biopsies of areas that look abnormal and use them to detect cancer, precancerous cells, infections, and other conditions. Endometriosis tissue can also form on the bowel, the peritoneum (membranous lining of the abdomen and covering the intestines), the cul-de-sac/pouch of Douglas (small area of the peritoneum between the uterus and rectum), the rectum, small intestines, or appendix.
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